Cerebral venous thrombosis

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[edit] Discussion of Cerebral venous thrombosis

  • Cerebral venous thrombosis is a relatively uncommon disorder (estimated annual incidence of between two and seven cases per million) in the general population.
  • Causal factors may be classified as:
    • Local: Related to intrinsic or mechanical conditions of the cerebral veins and dural sinuses (i.e. sinus trauma, mastoiditis, and neoplastic invasion or compression).
    • Systemic: Related to clinical conditions that promote thrombosis (i.e. protein S and protein C deficiencies, a peripartum state, oral contraceptive use, and hypercoagulable states secondary to malignancy).

  • The clinical manifestations of cerebral venous thrombosis vary, depending on the extent, location, and acuity of the venous thrombotic process as well as the adequacy of venous collateral circulation.
  • Intracranial hypertension occurs in 20%–40% of patients with cerebral venous thrombosis and should be excluded in patients with the specific complex of symptoms.

[edit] Imaging Findings for Cerebral venous thrombosis

[edit] CT

  • The classic finding of sinus thrombosis on unenhanced CT images is a hyperattenuating thrombus in the occluded sinus; however, hyperattenuation is present in only 25% of sinus thrombosis cases.
  • Increased attenuation in the venous sinuses also may be seen in patients with dehydration, an elevated hematocrit level, or a subjacent subarachnoid hemorrhage or subdural hematoma.

[edit] Images

Patient #1: Thrombosis of multiple sinuses

[edit] See Also

[edit] External Links

[edit] References for Cerebral venous thrombosis