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[edit] Discussion

  • Adenocarcinoma that arises from the bile duct epithelium.
  • Second most prevalent liver cancer after hepatocellular carcinoma.
  • Associations:
  • Usually classified as either intrahepatic or extrahepatic
    • Intrahepatic cholangiocarcinoma is further classified as either peripheral or hilar.
    • Tumor that arises from one of the hepatic ducts or the bifurcation of the common hepatic duct is considered to be hilar cholangiocarcinoma (Klatskin tumor).
  • M&M: most patients die within a year of diagnosis.

[edit] Imaging Findings

[edit] CT

  • Delayed enhancement
    • Delayed enhancement with increasing attenuation may be seen on images in as many as 74% of patients.
    • This pattern of enhancement may be useful in differentiating HCC from cholangiocarcinomas. HCC shows an early peak increase in attenuation with a progressive decrease.
  • The overlying liver capsule may be retracted when the lesions are peripheral.

[edit] Images

Patient #1: Delayed enhanced CT images demonstrate cholangiocarcinoma in the right hepatic lobe.

[edit] See Also

[edit] External Links

[edit] References

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