From RadsWiki

Jump to: navigation, search


[edit] Discussion of Osteopoikilosis

  • Osteopoikilosis is AKA osteopathia condensans disseminata and "spotted bone disease"
  • Osteopoikilosis is an asymptomatic disorder
  • Characterized by an abnormality in the enchondral bone maturation process that results in numerous round 2-10 mm bone islands, that are symmetrically distributed within the metaphyses and epiphyses of the long bones,
  • Lesions appears in childhood and persists throughout life.

  • It may either be inherited in an autosomal dominant fashion or occur sporadically.
  • Men and Women are equally affected.
  • Sites of predilection include hands, feet, pelvis, and femur.
  • The ribs, skull and vertebrae are typically spared.

  • Some patients have connective tissue nevi called dermatofibrosis lenticularis disseminata.
  • Osteopoikilosis have also been found to be associated with a tendency to keloid formation, dwarfism, spinal stenosis, dystocia, melorheostosis, tuberous sclerosis and scleroderma.

  • Its major clinical significance is that it should not be confused with metastatic osteoblastic lesions.

[edit] Imaging Findings for Osteopoikilosis

  • On radiography, small, well-defined, ovoid foci of increased radio density are clustered in periarticular osseous regions.

[edit] Images

Patient #1

[edit] See Also

[edit] External Links

[edit] References for Osteopoikilosis