Transposition of great arteries

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[edit] Discussion of Transposition of great arteries

  • Transposition of the great arteries is the most common cyanotic congenital heart lesion found in neonates
  • It accounts for 5%–7% of congenital cardiac malformations.
  • It is most common in infants of diabetic mothers.
  • It is isolated in 90% of those affected and rarely is associated with a syndrome or an extracardiac malformation.

  • Transposition of the great arteries is produced by a ventriculoarterial discordance in which the aorta arises from the morphologic right ventricle and the pulmonary artery arises from the morphologic left ventricle.
  • To sustain life, a communication (eg, a patent foramen ovale, atrial septal defect, ventricular septal defect, or a combination of these) must be present between the systemic and the pulmonary circulation, in addition to systemic collateral arteries.

[edit] Imaging Findings for Transposition of great arteries

  • In the normal anatomy, the aorta is anterior to and at the right of the pulmonary artery
  • In transposition of the great arteries, the pulmonary artery is situated to the right of its normal location and is obscured by the aorta on frontal chest radiographs.
  • This malposition, in association with stress-induced thymic atrophy and hyperinflated lungs, results in the apparent narrowing of the superior mediastinum on radiographs, the most consistent sign of transposition of the great arteries.
  • The cardiovascular silhouette varies from normal in the first few days after birth to enlarged and globular, with the classic egg on a string appearance.

[edit] Images

Patient #1

[edit] See Also

[edit] External Links

[edit] References for Transposition of great arteries