Varicella pneumonia

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[edit] Discussion

  • Varicella-zoster virus pneumonia is the most serious complication of disseminated varicella-zoster virus infection with mortality rates of 9%–50%.
  • Varicella-zoster virus most commonly causes self-limited benign disease (chickenpox) in children. However, in adults it tends to cause significant complications such as varicella-zoster virus pneumonia.
  • More than 90% of cases of varicella-zoster virus pneumonia in adults occur in patients with lymphoma and immunocompromised patients.
  • Histologic features of varicella-zoster virus pneumonia are those of diffuse alveolar damage. With recovery from the initial disease, spherical nodules are seen, scattered randomly throughout the lung parenchyma.

[edit] Imaging Findings

[edit] Plain film

  • Multiple 5–10-mm ill-defined nodules that may be confluent and fleeting.
  • Small, round nodules usually resolve within a week after the disappearance of the skin lesions but may persist for months.
  • Lesions can calcify and can persist as numerous, well-defined, randomly scattered, 2–3-mm dense calcifications.

[edit] CT

  • Well-defined and ill-defined nodules diffusely throughout both lungs.
  • Nodules with a surrounding halo of ground-glass opacity, patchy ground-glass opacity, and coalescence of nodules are also seen.

[edit] Images

Patient #1

[edit] See Also

[edit] External Links

[edit] References